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apalutamide will reduce the extent or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a strong CYP2C19 inducer, with medications which have been CYP2C19 substrates can result in reduced publicity to these remedies.diazepam will boost the amount or result of